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Oregon passed a first-of-its-kind measure to formally legalize access to hallucinogenic mushrooms. Specifically, Measure 109 directs the state to establish and regulate a program whereby adults in the state will be able to consume psilocybin, a psychoactive compound found in magic mushrooms.

A study of adults with major depressive disorder (MDD) by Johns Hopkins Medicine researchers has found that two doses of a psychedelic compound found in “magic mushrooms,” can produce large reductions in depressive symptoms, when administered with supportive psychotherapy.

For the entire group of 24 participants, 67% showed a more than 50% reduction in depression symptoms at the one-week follow-up and 71% at the four-week follow-up. Overall, four weeks post-treatment, 54% of participants were considered in remission—meaning they no longer qualified as being depressed.

“The magnitude of the effect we saw was about four times larger than what clinical trials have shown for traditional antidepressants on the market,” said Alan Davis, PhD, adjunct assistant professor of psychiatry and behavioral sciences at the Johns Hopkins University School of Medicine.

Source: Mother Jones/GenEngNews